Indole-3-carbinol
Molecular Formula： C9H9NO
Molecular Weight：147.1739
Assay：98%
Country of Origin：China
Shelf Life：2 Years
|
Product Name |
CAS No. | Content |
Testing |
|
Indole-3-carbinol
|
700-06-1 |
98% | HPLC |
Product description:
Indole-3-carbinol is a tumor chemopreventive substance that can be extracted from cruciferous vegetables such as broccoli, radish, and cauliflower.
Specification:
| ITEMS | SPECIFICATION |
| Appearance | White to grayish white crystals |
| Loss on Drying | <1% |
| Residue on Ignition | <0.1% |
| Purity(HPLC) | ≥98% |
| Heavy Metal | ≤10mg/kg |
| Lead(Pb)，mg/kg | ≤0.5 |
| Mercury(Hg)，mg/kg | ≤0.5 |
| Cadmium(CD),mg/kg | ≤0.5 |
| Arsenic(AC),mg/kg | ≤0.5 |
| methanal | ≤0.3% |
| ethanal | ≤0.5% |
| ethyl acetate | ≤0.5% |
| Total plate count | ≤10000 cfu/g |
| Yeast&Mold | ≤300 cfu/g |
| Ecoli |
Negative |
|
Salmonella |
Negative |
Function:
1. Anti hormone like activity indole-3-carbinol can increase the activity of cytochrome P4501A and affect the metabolic pathway of estrogen, increase the activity of estradiol 2-hydroxylase and the metabolic level of catechol pathway, thereby increasing the level of 2-hydroxyestrone in hormones. Indole-3-methanol is also reduced by 16 α- The hydroxyl estrogen pathway is used to reduce the stimulation of female glands, exert hormone like activity, and inhibit certain estrogen dependent tumors.
2. Inhibiting the binding of carcinogens to DNA with indole-3-carbinol can prevent the binding of aflatoxin AFB1 to DNA and inhibit the mutagenic effect of AFB1 on organisms. Indole-3-carbinol inhibits the binding of carcinogenic DNA adducts related to cigarette smoke.
3. Regulating the activity of metabolic enzymes in the body, indole-3-carbinol can induce the activity of drug metabolic enzymes in Phase I and Phase II, increase the activity of glutathione in tissues and target organs, and transcriptionally induce the activity of glutathione S-transferase (GST), epoxide hydrolase, and quinone oxidoreductase NAD (P) H, participating in the detoxification of electrophilics, protecting cells from oxidative damage and playing an anticancer role.
Packaging Details
Packing
Packed in paper-drums and two plastic-bags inside.
For minimal quantity
1 kg/aluminium foil bag, 5 bags in a carton.
For large quantity
25 kg/fiber drum in net weight; 28 kg/fiber drum in gross weight (can be customized).
Other
Storage condition: Stored in a well-sealed container in a dry, cool place, keep away from strong light and heat.
Shelf life: 24 months under the conditions above and in its original packaging.
